Group Isolation and Atherosclerosis in Cholesterol-Fed Cockerels

Group Isolation and Atherosclerosis in Cholesterol-fed Cockerels.

• It has been suggested that emotional stresses may be involved in the rate of development of atherosclerosis, may act to precipitate an acute arterial occlusion in the presence of atherosclerotic vascular disease, or, in the case of muscular organs like the heart, may serve to enhance the rate of activity of the organ beyond the capacity of the vasculature to prevent acute ischemia, thereby tr...

Effect of exercise on blood coagulation time and atherosclerosis of cholesterol-fed cockerels.

Influence of MER-29 on experimental atherosclerosis of cholesterol-fed cockerels.

• It has been reported that MER-29, 1[(4-diethylaminoethoxy) phenylj-l-(p-tolyl)2-(p-chlorophenyl) ethauol, significantly lowers both serum and tissue cholesterol in rats and humans." Further investigation has demonstrated that drug-inhibited cholesterol synthesis in the body was due primarily to a block in a late stage of cholesterol synthesis. The present study was undertaken to study the eff...

Reversibility of atherosclerosis in cholesterol-fed rabbits.

Previous studies have attempted to demonstrate the reversibility of rabbit atherosclerosis after discontinuance of cholesterol feeding or by other measures. These attempts have been largely unsuccessful. In all the studies, atherosclerosis was induced by cholesterol feeding for several months. At the end of these prolonged periods, the animals had advanced aortic lesions. The present study soug...

Effects of dietary proteins, methionine and vitamins on plasma lipids and atherogenesis in cholesterol-fed cockerels.

Methionine deficiency in the presence of a high-fat, high-cholesterol diet aggravates atherogenesis in the cockerel. High-protein, high-vitamin supplementation suppresses the atherogenic effect of a cholesterol-fat-containiiig diet. High-protein supplementation alone had a suppressive effect; high-vitamin supplementation had no effect. However, the combined protein and vitamin supplement was th...